Please find the Spring 2015 edition of the PHE Birmingham Newsletter here

New guidelines on the interpretation of troponin are in use from today. These guidelines take into account gender specific differences in troponin measurements to increase the diagnostic accuracy. For further guidance see: https://heftpathology.site/item/troponin-i-2.html

Please find the January 2015 edition of the PHE Birmingham Newsletter here

Paroxysmal Nocturnal Haemoglobinuria (PNH) is an acquired haematopoietic stem cell disorder resulting in a partial or total deficiency of proteins normally linked to cell membranes by a glycosylphosphatidylinositol (GPI) anchor. Classical features are;

• intravascular haemolysis
• bone marrow failure
• thrombotic tendency
• may also include abdominal pain, dysphagia, erectile dysfunction, renal failure, lethargy

It can often go undiagnosed for months or even years. Flow cytometry can provide a definitive diagnosis.

Click here for further guidance on PNH testing. Contact the laboratory on 0121 424 0704.

New guidance on action to take on finding a monoclonal protein can be found here.